Current update on combined hepatocellular-cholangiocarcinoma

نویسندگان

  • Suresh Maximin
  • Dhakshina Moorthy Ganeshan
  • Alampady K. Shanbhogue
  • Manjiri K. Dighe
  • Matthew M. Yeh
  • Orpheus Kolokythas
  • Puneet Bhargava
  • Neeraj Lalwani
چکیده

Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology. Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked with cholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present with an more aggressive behavior and a poorer prognosis than either hepatocellular carcinoma or cholangiocarcinoma. An accurate preoperative diagnosis and aggressive treatment planning can play crucial roles in appropriate patient management.

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عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2014